This 39-year-old white male developed RSD / CRPS in the left lower extremity following a fracture in 2005. Currently, there is spreading pain to the right lower extremity.

Following the 3-day, 4-hour ketamine infusions there was improvement in pain thresholds (below) associated with improved ability to walk, improved sleep and decrease depression.

The vital signs were stable throughout the 3-day infusion. There was occasional slight nausea during the infusion.

The patient’s clinical outcome and treatment plan was document in a video recording. The patient was provided a copy of the pre-treatment and post-treatment videos.

ADDENDUM POST TREATMENT:

The patient tolerated up to 200 mg per hour of ketamine, limited slightly by respiratory depression.  Post-infusion, the patient had a single episode of dysphoria after infusion #3 which was prevented for treatment #4 by pretreatment with 2 mg Versed at the end of the 4-hour infusion.  The patient had significant improvement in pain thresholds and range of movement in all extremeties. 

ADDENDUM POST TREATMENT:

The patient tolerated up to 200mg an hour of ketamine with stable vital signs and no nausea or vomiting, limited by possibility of respiratory depression.

The patient experienced an overall improvement in pain thresholds.